Properties and potential applications of syngeneic monoclonal anti-idiotypic antibodies: use as a reference standard in enzyme-linked immunosorbent assay

Reference Report for IND91018502

Title:	Properties and potential applications of syngeneic monoclonal anti-idiotypic antibodies: use as a reference standard in enzyme-linked immunosorbent assay
Authors:	Mernaugh, R.L., Hill, J.H., Durand, D.P., Van-Deusen, R.A., Harris, K.F.
Source:	Phytopath. 1991, 81(3):274-282
Abstract:	Syngeneic anti-idiotypic monoclonal antibodies were generated to an anti-soybean mosaic virus (SMV) monoclonal antibody. One of these antibodies (1a) was used in place of SMV to capture rabbit polyclonal anti-SMV antibodies in an enzyme-linked immunosorbent assay (ELISA). This demonstrated that an anti-idiotypic monoclonal antibody can be used as a standard in ELISA for detection of exotic pathogens when conditions preclude introduction of the pathogen into the environment

Funded by the USDA-ARS. Developed by the USDA-ARS SoyBase and Legume Clade Database group at the Iowa State University, Ames, IA

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